Celastrol CAS 34157-83-0

CAS:34157-83-0

Fa'asologa Molekiula:C29H38O4

Mamafa Molekiula:450.61

EINECS:636-472-5

Upu tutusa:CELASTROL(SH); CELASTROL; Celastrol (Tripterin); CELASTROL(P)(FA'AMOLEMOLE VALA'AU MAI); (20R)-3-Hydroxy-2-oxo-24-nor-D:A-friedoolean-1(10),3,5,7-tetren-29-oic acid; 2-Oxo-3-hydroxy-24-norfriedela-1(10),3,5,7-tetraene-29-oic acid; 2-Oxo-3-hydroxy-24-norfriedelane-1(10),3,5,7-tetraene-29-oic acidCelasterol

Tu'u Lau Savali

Fa'amatalaga o le oloa

La'uina mai

Fa'ailoga o Oloa

O le ā le Celastrol CAS 34157-83-0?

E lē solo le Celastrol i le vai, ae solo i le dimethyl sulfoxide ma le anhydrous ethanol. E maua mai i mea e tete'e atu ai i le kanesa i la'au e pei o le Thunder God Vine ma le South Snake Vine i le aiga o Celastraceae. O se vaila'au e taofia ai le proteasome, ua fa'amaonia e fa'aosofia ai le apoptosis o sela o le kanesa e ala i le taofia o le gaioiga o le proteasome.

Fa'amatalaga

Mea	Fa'amatalaga
Pula le tulaga	645.7±55.0 °C (Valoaina)
Mafiafia	1.2
Tulaga e liusuavai ai	219-230°C
pKa	4.78±0.70 (Vavaloina)
λmax	424nm(MeOH)(tusitusiga)
Tuutuuga o le teuina	-20°C

Talosaga

E fa'aaogaina le Celastrol mo le fuafuaina/fa'ailoaina o mea o lo'o i totonu/fa'ata'ita'iga fa'afoma'i, ma isi. A'afiaga fa'afoma'i: E iai ona meatotino malolosi e tete'e ai i le fa'ama'i, aafiaga e tete'e ai i le kanesa, ma aafiaga e tete'e ai i le rheumatoid. O se mea e taofia ai le proteasome, ua fa'amaonia e fa'aosofia ai le apoptosis o sela kanesa e ala i le taofia o le gaioiga o le proteasome.